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JOURNAL OF PREVENTIVE MEDICINE
ISSN:
1582-5388
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Editorial Elena Lungu The exercise of writing goals and objectives
helps to focus how the activity and vision will be achieved. Goals are
specific and measurable components. Meeting them, mean that the program is
successful and the vision achieved. For each goal, there is a list of
objectives that must be achieved in order to reach the goal. Millennium development goals are the most
recent statement of commitment towards
health and human development (1). The Millennium
Development Goals (MDGs), adopted by the United Nations in 2000, provide an opportunity for action in order to improve
global health. They place health at a central issue of development and
establish goals at a global level, linking
developed and developing countries through clear, reciprocal obligations (2).
Ü FULL
TEXT.PDF Health patterns and determinants Elżbieta
Pac-Kożuchowska Abstract. Aim: The evaluation of lipid parameters, homocysteine, soluble adhesion
molecules in the blood serum and the thickness of common carotid artery wall
in children from families with diagnosed risk factors of atherosclerosis.
Material and methods: The
study included 18 children (8 girls and 10 boys) aged 2-3 years and their
parents from families with circulatory system disease in their history. The
control group was composed of 16 children (8 girls and 8 boys) aged 2-3 years
from families without that risk. In all of the subjects concentrations of
triglycerides, total cholesterol and its fractions: LDL, VLDL, HDL and of
apolipoproteins (apo-AI, apo-B), lipoprotein (a), homocysteine as well as of sICAM-1 (intracellular
adhesion molecule-1), sVCAM-1 (vascular cell adhesion molecule-1) and sE-selectin in the blood serum were
determined. The intima-media thickness (IMT) measurement was made with
ultrasonographic method in children and their parents from families with positive
history and in children from families with negative history.
Results: The
concentration of triglycerides, VLDL cholesterol and lipoprotein (a) had the
highest value in the blood serum of the children from the families with risk
factors of atherosclerosis as compared to the levels of the children from
families without that risk and the differences were statistically significant
(p<0.05). The evaluation of the relationship between the IMT and lipids,
lipoproteins, apolipoproteins, homocysteine and soluble adhesion molecules in
children from families with risk of cardiac ischaemia and in children from
control group did not confirm any significant statistically correlations. The
statistically significant positive correlation was confirmed between IMT and total
cholesterol in mothers and between IMT and apo-B in fathers from families
with positive history. Conclusion: The significant increase in the
concentrations of triglycerides, VLDL and lipoprotein (a) in children with
positive family history of atherosclerosis risk indicates that this group is
particularly exposed to early atherosclerotic changes. We are planning to
continue the research in this group of children in order to find the
atherosclerosis risk factors.
Key words: lipids,
lipoprotein (a), homocysteine, adhesion molecules, IMT,
atherosclerosis risk factors Ü FULL
TEXT.PDF Age standardized
mortality rates by occupational classes and causes of death in Cluj Napoca Ligia Făt, A. Cocârlă, S. Ţigan Abstract:
A cohort mortality study was completed using details from death records and
occupations of 2893 persons who died in the city of Cluj Napoca in the year
2002. The level of mortality by occupational class was expressed by
Standardized Mortality Ratios (SMR) with national death rates by 15-year age
group as the standard. Each occupation has been assigned to one Social Class
according to the British Classification of the Social Classes in 6 different
categories. Causes of death were coded according to the International
Classification of Diseases, 10th Revision WHO. The data were
collected in the Microsoft Excel program and were statistically analyzed
using the EXCEL and EPIINFO programs. The overall mortality of the all social
classes were significantly lower than expected, especially in 15-30 and 30-45
groups of age. Significant mortality increase was recorded at ages 45-60 for
the social classes IV and V, while the other social classes still show
significant mortality deficits. At ages >60 only the social classes I and
II show significant mortality deficits, while the social classes III(N) to V
have a significant mortality increase with excess mortality. There was a
widening difference between social classes I and II and the other social
classes for all causes of mortality at ages 45–60 and >60. This was
particularly marked for social class V. In particular, for specific causes of
death, at ages 15-30, the SMR was higher in social classes IV and V. The
values of SMR increase at ages 30-45, with the highest values in the same
social classes IV and V for all selected causes. A similar pattern of
increasing mortality with declining social class was clearly demonstrated for
each of the selected causes at ages 45-60 with a big difference in mortality
between the top and the bottom of the social class scale. For all selected
causes there was a sharp step in the gradient between classes IV and V and
the other classes. At ages >60 this sharp step appears between class I and
II and the other classes.
Keywords: age-standardized mortality rates, social classes,
cardiovascular disease, cerebrovascular disease, cancer Ü FULL
TEXT.PDF Patient dose from conventional diagnostic radiology
procedures in Serbia and Montenegro Olivera Ciraj, Srpko Marković, Duško
Košutić Abstract. The objective was to assess the patient doses for most frequent X-ray
examinations in Key
words: X-rays, diagnostic radiology, entrance surface
dose, effective dose, optimisation Ü FULL
TEXT.PDF Cultural and biochemical
characteristics of Acinetobacter
spp. strains isolated from hospital units Sofia Constantiniu, Angela Romaniuc,
Luminiţa Smaranda Iancu, Raluca Filimon, Iuliana Taraşi Abstract. The A.
baumanii and A. lwoffii
strains, isolated from clinical and environment samples in hospital units,
were investigated from the biochemical characteristics and their
susceptibility to antimicrobial agent points of view. The nonfermenter,
Gram-negative coccobacilli were
classified in A. baumanii and A. lwoffii species on the basis of
the catalase positive, oxidase
negative, nonmotility, the fermentative/oxidative test and utilization of
nutritive substrates. The percentages of susceptibility to antimicrobial
agents varied according to the class of antimicrobial drugs. Only 16.6% of
strains were sensitive to ampicillin, 25% to ceftriaxone, ceftazidime,
gentamicin and kanamycin. Most of the strains
were sensitive to ciprofloxacin
and to imipenem (83.3% and 91.6% respectively). Key-words:
Acinetobacter, strains, biochemical
characteristics, susceptibility, antibiotics
Ü FULL
TEXT.PDF Mihaela Zlei,
Octăviţa Ailiesei, E. Carasevici Abstract. The
incidence of human listeriosis is sporadic, but we previously demonstrated
that T lymphocytes with reactivity to Listeria
monocytogenes are with a high frequency in healthy individuals. As
kinetics of specific expansion within CD4+ and CD8+ T cell compartments is
particular to a certain pathogen, we attempted to describe the peculiarities
which define the T cell reactivity to L.
monocytogenes in humans. Our results demonstrated that, although the
proliferative response of the two categories of T cells was broadly
synchronized, there was a striking difference in the magnitude of the two
types of response, when compared. The differential maintenance of the
antilisteric memory T cell subsets in the periphery, suggested by our study,
generated a set of alternative issues which are discussed below. Key
words: listeria, humans, CD4/CD8
T cells, proliferation,
flow-cytometry, CFSE Ü FULL
TEXT.PDF Nonspecific immunological
aspects related to silicosis
O.
Persecă, A. Cocârlă Abstract. The aim of the study is to analyse the profile of
the non-specific systemic immune response in a group of subjects with
silicosis, that have variable opacities profusion on standard chest X-ray,
and to try an estimate of the immune aggression in silicosis, to find a
possible association of the humoral immunological parameters with the
silicosis evolution stages as a criteria for the disease progression. A group
of 68 male
patients with occupational exposure to crystalline silica was investigated,
compared with a control group, 35 male healthy
subjects, non-exposed. Humoral immunity parameters, IgA, IgG, IgM, C3
complement and circulating immune complexes (CIC) were determined
using immunochemical methods. It was observed that immunoglobulin levels
presented a polyclonal increase. C3 complement levels were within reference
values. CIC presented elevated mean values two fold higher for the late
stages of silicosis. The obtained data show a hyperreactivity of the humoral
mediated immunity in silicosis, but these parameters could not be used as
predictive criteria for the disease progression. Key
words:
silicosis, humoral immunity Ü FULL
TEXT.PDF Flowcytometric
evidence of DNA ploidy in human breast cancer Dorina Munteanu, Mihaela Zlei, Octăviţa
Ailiesei, Camelia Chifu, C. Diaconu, E. Carasevici Abstract. Breast cancer is the most common form of
malignancy that affect women. Tumor proliferation can be monitored by
measuring DNA synthesis using flow cytometry which provides rapid and precise
analysis of large numbers of cells. The aim of the present study was to
evaluate DNA ploidy in breast cancer and its relationship to other classical
clinico-pathological parameters (age, tumor size, histological type, grade of
cellular differentiation, lymph node status). This study was initiated in
September of 2003 and continued until April of 2004. A number of 30 patients
diagnosed with mammary carcinoma and subjected to surgery at the III-rd
Surgical Clinic of the “Sf. Spiridon” Hospital were taken into
consideration.. None of the patients were subjected to chemo- or
radio-therapy prior to surgery. Cell cycle analyses were performed with fresh
tumour sample and normal tissue surrounding the tumour. Data were analysed by
Modfit (Verity Software House, Key words: ploidy,
flowcytometry, breast cancer
Ü FULL
TEXT.PDF Dermatoglyphic research in
ophthalmic disorders Ana Ţarcă
Abstract.
The present paper consists
of a study on dermatoglyphics pathology on a lot of 200 patients, blind or
suffering from other severe ophthalmic disorders (100 men and 100 women) from
Key words: dermatoglyphics, blind people, ocular
affections, abnormalities or distortions
Ü FULL
TEXT.PDF Methanol
poisoning risk of aspartanic containing-cooling drinks consumers Codruţa Petrişor, J.
Máthé Abstract. Methanol, the chemical
compound with very noxious effects on human organism, is included in
food-stuffs and pharmaceutical products. Thus, the risk of poisoning by
methanol exists by the consumption of products with sugar substituted by
aspartame (food additive E951) because it occurs promptly by aspartame
hydrolysis in physiological condition. Considering the above reasons, we have
proposed the methanol dosage in the distillate of cooling beverages from the
light group (including aspartame) and the results correlation with their
aspartame concentrations. The chromatografic method was used in order to
separate the aspartame and the distillation for methanol separation. Both for
methanol and aspartame dosage,
spectrophotometric methods were utilized. The aspartame and methanol
concentrations determined in our study are higher than those reported by the
international organizations such as Food & Drugs Administration and
Nutrasweet (FDA) and this is why the authors consider the necessity of
population warning about the health risks associated with the current
ingestion of aspartame containing - products. Taking into account that
aspartame is quite cheap and it has a sweetening power of 200 times higher
than sugar, its use persists in over than 9000 products, despite the 92
neurological, ophthalmic and immunological symptoms reported by FDA in 1993.
Key
words: methanol, aspartame, sweetening food additive Ü FULL
TEXT.PDF Dental health Evaluation
of calcium concentration in solution - in
vitro study of fluoride action on dental enamel Monica Păruş, Şt.
Lăcătuşu, Abstract. In the present study the mineral loss/gain
(ΔCa) in dental enamel during de-/ remineralization process, depending
on used fluoride concentration, were measured in vitro in pH cycling conditions. 20 sound premolars extracted
for orthodontic reasons were divided in 4 subgroups. Artificial lesions were
created on each of them. They were all subject to a pH cycling regimen for 2
weeks. During the pH cycling regimen each of the 4 subgroups received
different treatment: Placebo paste, fluoride tooth paste (1440 ppm F),
fluoride gel (12,000 ppm F), and rinsing solution (227 ppm F). Calcium
concentration in de-/remineralization solution at the beginning and at the
end of the study was determined using the spectrometer with atomic
absorption. The relative succession of the fluoride containing products in
terms of efficiency was established to be: fluoride tooth paste ≥
fluoride rinse > fluoride gel. Key
words: fluoride, calcium, dental enamel, prevention Ü FULL
TEXT.PDF Abstracts „THE SECOND ROMANIAN-GERMAN SYMPOSIUM ON OCCUPATIONAL
MEDICINE” |
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