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JOURNAL OF PREVENTIVE MEDICINE ISSN: 1582-5388
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C O N T E N T S Public health Project
management –a way of reducing uncertainties Elena Lungu Abstract. Projects and project
management operate in an environment broader than that of the project it
self. A project is often regarded as a desired goal, which can be realized
with the available means. In this sense we try to increase our chances and
minimize the risks. This article comprises
concepts, principles, models of project management and different stages of a
project. Key words: project,
project management, product-market combinations, concepts, principles, models Ü FULL TEXT.PDF Trend of methemoglobinemia cases in eastern Romania Marieta Vasilov, St.Condrea, Anca Cristea, A.Chiroşcă, Antoneta Dobreanu, Aurora Georgescu, Elena Şerban, Elena Vrabie Abstract. The results of an epidemiological
descriptive study based on the cases reported by the Districtual Public Health Departments are presented. The incidence
of methemoglobinemia rates in 0-1 years aged infants varied between 1.5 o/oo
and 7.0 o/oo during 1996-2000 in eastern Key words: infants,
methomoglobinemia cases, nitrites, nitrates in water, descriptive epidemiology
Ü FULL TEXT.PDF
A follow-back of men and
women who grew up in Romanian orphanages N. Lie, D. Murăraşu Abstract.
Abandonment and
institutionalization were studied retrospectively in 55 men and 20 women who
had grow up in orphanages. The major causes of abandonment was being born by
a single/unmarried mother or by poor parents. Family adversity and parental
dysfunction was the major cause of only one fourth of the abandonments. More
than half of abandoned children were admitted during the first six months of
life, and only one quarter after age three. The average time spent in
orphanages was 14 years for boys and 17 years for girls. No more than 25% of
the boys and 12% of the girls were keeping in contact with the family during
in-care. As many as 73% of the boys and 41% of the girls were physically
abused and 23% of the girls and 17% of the boys were sexually abused in the
orphanage. Key
words: abandonment of children, institutionalized children, physical abuse,
sexual abuse, orphanages, dystrophics Ü FULL
TEXT.PDF Parental dermatoglyphic aspects in
trisomy 21
Ana Ţarcă
Abstract. The paper deals with an analysis of
digito-palmar dermatoglyphics with the parents of 54 children with Trisomy 21
(Down Syndrome) studied before [15]. The results obtained confirm the data
found in the foreign specialised literature according to which many of the
dermatoglyphic malformations present at children with Trisomy 21 can also be
found to their apparently healthy parents but in a smaller number, because
here they signal only the presence of the Trisomy 21 (partial Trisomy 21,
Trisomy 21 by balanced translocation or mosaic Trisomy 21) while in the case
of the affected children these abnormalities are also the graphic expression
of the multiple malformations that accompany their total or unbalanced
translocation Trisomy 21. Consequently, the author considers that the
dermatoglyphic distortions illustrated in both cases (parents and their
children), could be used as pathological indicators in the identifying of the
carrier persons of the inapparent phenotypically Trisomy 21 but having the
risk of giving birth to children with complete Trisomy 21 and specific
multiple malformations. Key words: Dermatoglyphics,
Trisomy 21 (Down Syndrome), distortions (anomalies) Ü FULL
TEXT.PDF Antioxidant enzyme levels in reactive arthritis and
rheumatoid polyarthritis Irina Popovici, Elena Rezuş, Gabriela Mancaş Abstract. This study is based on the comparative
analysis of 38 patients with reactive arthritis defined by Amor criteria, a
group of 33 patients with rheumatoid polyarthritis and 50 healthy controls.
Antioxidant systems (glutathione peroxidase, superoxide dismutase,
catalase) were investigated in
inflammation consecutive to immune and infectious syndromes. Our study showed
that reactive arthritis and rheumatoid arthritis is associated with enhanced
oxidative stress. The lower levels of natural blood antioxidant enzyme, were
related to severe forms of disease. The investigation of oxidative metabolism
lies at the basis of antioxidant therapy that could influence the natural
course of reactive arthritis and polyarthritis. Key words: reactive arthritis, rheumatoid
poyarthritis, oxidative stress, oxygen free radicals, catalase, glutathione peroxidase, superoxide
dismutase Ü FULL TEXT.PDF
Epidemiology: communicable
diseases Trends of leptospirosis in
eastern counties of Romania during the past two decades Angela Romaniuc, Raluca Mihaela
Filimon, Anca Nistor, Mariana Virlan, Mihaela Debita, Elena Duca, Anca
Dancau, Roxana Pipirigeanu, Marina Maiorov, Ecaterina Chihaia, V. Morariu
Abstract. Leptospirosis is a zooanthroponosis with major
implication for the public health. The incidence of the disease rises during
the last decade in eastern counties of Romania. The change that occurred in
agricultural sector brought mutations in the epidemiological process.
Leptospirosis registered during past years a trend to dispersion the rural area.
There are involved all the active age group in close relation into
occupational hazards (plumbers, animal breeders). The clinical evolution of
the disease is a sever one (21%) with a fatality rate of 4.5% and the
specific mortality of 0.14 o/oooo. The incriminated
serotypes found were: L. icterohaemorrhagiae, wolffi and gryppotyphosa.
An efficient leptospirosis control needs a better collaboration between
veterinary and human medical network. Key words: leptospirosis,
epidemiology, clinic symptoms, diagnosis, prevention and control Ü FULL
TEXT.PDF Elie Shlyakhov, Alla Vâţă, Efim Platkov Abstract:
this review presents many of numerous studies realized in the past century by
romanian researchers who contributed directly or indirectly to progress in
animal anthrax specific prevention and imunological diagnosis of the disease.
It is underlined nicolae stamatin’s great contribution; he obtained a new
acapsulated and attenuated vaccinal strain of b. Anthracis whose mass use led to a dramatical decrease of
anthrax morbidity among animals. Many studies were performed to
achieve an immunological diagnosis of the disease. The review highlights the
studies performed by shlyakhov et al. On laboratory diagnosis of patients
which are culture negative because of previous antibacterial therapy. The
intradermal testing with anthraxin extracted from acapsulated vaccinal strain
of b. Anthracis by shlyakhov et al.
Offers the possibility to asses the cell mediated immunity. Anthraxin-like
products adapted for elisa will be able to reveal, in vitro, the cellular immunity in vaccinated animals. Keywords: anthrax, vaccine,
immunological diagnosis Ü FULL
TEXT.PDF
Experimental
research Henryk ZielińskiAbstract. In this study we examined the impact of carbon black particles (CBPs) type M120 on
the reduced glutathione and proteins in the respiratory tract epithelial
lining fluid (ELF) using a model exposure system. Model ELF solutions without (-) and with
(+) chelating agents were incubated with 500 mg/mL of CBPs in 1 mL aliquots
(37oC) for 0-6h under mixed conditions. At set intervals
throughout the exposure, CBPs were removed by centrifugation, and samples
rapidly frozen prior to reduced glutathione (GSH), proteins and protein thiols
determination. It has been demonstrated that both albumin and chelating
agents can protect oxidation of reduced glutathione induced by carbon black
particles. Key words: air
pollutants, respiratory tract lining fluid, albumin, reduced glutathione, proteins
thiols Ü FULL TEXT.PDF Luminiţa Jerca, Irina Popovici, Oltiţa Jerca, Florina Filip, Nastasia Gheorghiţă, Al.T.Balaban Abstract. Attempts have made to characterize the
antioxidant potential of the early phase of bronchial asthma. An experimental
model trying to mimic allergic bronchial asthma was immunologically induced
with ovalbumin (OA) in guinea pigs which were then treated with a NO donor
(ammonium salt of N- nitrosophenyl-N-hydroxilamine) at a concentration of 0,1
mg/Kg (1/400 of DL50) for 2 weeks. The animals were killed afterwards, for
assessing the presence of cellular oxidative stress and free radicals (FR).
The changes in the activity of superoxide-dismutase (SOD),
glutathione-peroxidase (GPx), reduced glutathione (GSH) and malon-dialdehide
(MDA), were followed in the heparinized blood of guinea pigs series (5-6
animals in series): L1 = nebulized with OA; L2 = hypersensitized with OA; L3
= hypersensitized with OA and treated intraperitoneal for 2 weeks with NO
donor; L4 = controls, healthy guinea pigs. The final data have revealed: The increased activity of SOD at series L3
compared to series L1 (+120.79 %) and to series L2 (+69.95 %) becoming closer
to the activity of the control series; the increased activity of GPx at series L3, compared to
series L1 (+2.48 %), to series L2 (+24.77 %) and to series L4 (+8.64 %); the
decreased level of GSH at series L3, compared to series L2 (-22.18 %) and to
series L1 (-15.83 %), but with an increased level compared to series L4 (+
36.85 %); the decreased concentration of MDA at series L3 compared to series
L1 (-6.52 %), to series L2 (-17,64 %) and to series L4 (-9.40 %), all these
proving a lower level of the lipid peroxides and damaging free radicals. The
positive effect of the NO- donor, with the above specific concentration, is
due to the stimulation of the synthesis of the oxidative stress biomarkers
which have an important antioxidant rol. Key
words: nitric oxide (NO),
superoxide-dismutase (SOD), glutathione-peroxidase (GPx), malon-dialdehide
(MDA), S-nitroso-glutathione (S-NO-GSH), bronchial asthma, oxidative stress
Ü FULL
TEXT.PDF History
of medicine Prophylaxis of smallpox in
Romanian traditional medicine Cristina Ionescu Variolation, as an empirical method of
smallpox prevention, was practiced since earliest times; it was first
mentioned in a Chinese medical textbook dated 1014, but it is presumed it was
in use throughout the Orient. Arabic people were familiar with rashes as
well as with the other infectious diseases. The famous physician Rhazes
(850-932) described smallpox and differentiated it from varicella and measles
in a paper nowadays considered as the first monograph in the medical
literature. Smallpox was also present in our country with epidemic waves
occurring from time to time. In the writings of the Romanian chroniclers no
devastating epidemic of smallpox similar to those recorded in |
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